ORAI2 anticorps (C-Term)
Aperçu rapide pour ORAI2 anticorps (C-Term) (ABIN500423)
Antigène
Voir toutes ORAI2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Specificité
- This antibody detects ORAI2 at C-term. It is predicted to have no cross-reactivity to ORAI1 or ORAI3.
-
Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse
-
Purification
- Peptide affinity chromatography
-
Immunogène
- ORAI2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ORAI2.
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS containing 0.02 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))
-
Autre désignation
- ORAI2
-
Sujet
- Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.Synonyms: C7orf19, CAP-binding protein complex-interacting protein 2, CBCIP2, Protein orai-2, TMEM142B, Transmembrane protein 142B
-
ID gène
- 80228
-
UniProt
- Q96SN7
Antigène
-