Haptoglobin anticorps (AA 251-350) (AbBy Fluor® 750)

N° du produit ABIN5004842

Cet anticorps anti-Haptoglobin est un anticorps Lapin Polyclonal détectant Haptoglobin dans WB, IF (p) et IF (cc). Adapté pour Humain, Rat et Souris.

Aperçu rapide pour Haptoglobin anticorps (AA 251-350) (AbBy Fluor® 750) (ABIN5004842)

Antigène: Haptoglobin (HP)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Haptoglobin est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-Haptoglobin anticorps (AbBy Fluor® 750)

Épitope: AA 251-350

Specificité: This protein may interact with Peptidase S1 Domain in LPA.

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Hpt

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Haptoglobin

Antigène: Haptoglobin (HP)

Autre désignation: Hpt/Haptoglobin

Sujet:

Synonyms: BP, HPA1S, HP2ALPHA2, Haptoglobin, Zonulin, HP

Background: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial, Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

ID gène: 3240

UniProt: P00738

Pathways: Transition Metal Ion Homeostasis