PLXDC2 anticorps (N-Term)
Aperçu rapide pour PLXDC2 anticorps (N-Term) (ABIN500515)
Antigène
Voir toutes PLXDC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Specificité
- This antibody detects Plxdc2 at N-term.
-
Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
-
Purification
- Peptide affinity chromatography
-
Immunogène
- Plxdc2 antibody was raised against a 18 amino acid peptide from near the amino terminus of human Plxdc2.
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS containing 0.02 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- PLXDC2 (Plexin Domain Containing 2 (PLXDC2))
-
Autre désignation
- PLXDC2 / TEM7R
-
Sujet
- Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57 % amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.Synonyms: Plexin domain-containing protein 2, Tumor endothelial marker 7-related protein
-
ID gène
- 84898
-
UniProt
- Q6UX71
Antigène
-