PRTFDC1 anticorps (Center)

N° du produit ABIN500545

Détail du produit anti-PRTFDC1 anticorps

Antigène: PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))

Épitope: Center

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRTFDC1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PRTFDC1.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: PRTFDC1 antibody was raised against a 14 amino acid peptide from near the center of human PRTFDC1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur PRTFDC1

Antigène: PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))

Autre désignation: PRTFDC1 (PRTFDC1 Produits)

Synonymes: anticorps HHGP, anticorps HPRT, anticorps hprt1, anticorps hprt1l, anticorps zgc:55561, anticorps zgc:86771, anticorps MGC80959, anticorps OTTMUSG00000011667, anticorps Prtfdc1, anticorps phosphoribosyl transferase domain containing 1, anticorps phosphoribosyl transferase domain containing 1 L homeolog, anticorps phosphoribosyltransferase domain containing 1 pseudogene, anticorps PRTFDC1, anticorps prtfdc1, anticorps Prtfdc1, anticorps prtfdc1.L, anticorps Gm13377

Sujet: Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.Synonyms: HHGP, Phosphoribosyltransferase domain-containing protein 1

ID gène: 56952

NCBI Accession: NP_064585

UniProt: Q9NRG1

Pathways: Ribonucleoside Biosynthetic Process