IRF6 anticorps (AbBy Fluor® 750)

N° du produit ABIN5005560

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF6 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour IRF6 anticorps (AbBy Fluor® 750) (ABIN5005560)

Antigène: IRF6 (Interferon Regulatory Factor 6 (IRF6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF6 est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB)

Détail du produit anti-IRF6 anticorps (AbBy Fluor® 750)

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IRF6

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur IRF6

Antigène: IRF6 (Interferon Regulatory Factor 6 (IRF6))

Autre désignation: IRF6

Sujet:

Synonyms: Interferon regulatory factor 6, IRF 6, IRF-6, IRF6, IRF6_HUMAN, LPS, OFC 6, OFC6, OTTHUMP00000034677, OTTHUMP00000034678, PIT, PPS, PPS1, VWS, VWS1.

Background: Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3 gamma p48 and IFN consensus sequence-binding protein (ICSBP).