RANBP10 anticorps (Center)

N° du produit ABIN500565

Détail du produit anti-RANBP10 anticorps

Antigène: RANBP10 (RAN Binding Protein 10 (RANBP10))

Épitope: Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RANBP10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: RANBP10 antibody was raised against a 15 amino acid peptide near the center of human RANBP10.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RANBP10

Antigène: RANBP10 (RAN Binding Protein 10 (RANBP10))

Autre désignation: RANBP10 (RANBP10 Produits)

Synonymes: anticorps RGD1311587, anticorps 4432417N03Rik, anticorps si:ch211-193l7.1, anticorps RAN binding protein 10, anticorps Ranbp10, anticorps RANBP10, anticorps ranbp10

Sujet: The RAN binding protein 10 (RANBP10) is a cytoplasmic guanine nucleotide exchange factor that shares high sequence similarity to the MET-interacting protein RANBP9. RANBP10 is expressed in the cytoplasm of mature megakaryocytes (MKs) and platelets where it localizes to polymerized noncentrosomal microtubules. RANBP10 possesses guanine nucleotide exchange factor activity towards RAN, a GTPase involved in nucleocytoplasmic traffic, spindle formation at mitosis, and nuclear envelope assembly during telophase, suggesting that RANBP10 may also be involved in these activities. RANBP10 depletion in vitro caused the disturbance of polymerized filaments in MKs and platelets in RANBP10-null mice exhibited disorders in microtubule filament numbers and localization, indicating that RANBP10 may play a significant role in maintaining microtubule dynamics.Synonyms: KIAA1464, Ran-binding protein 10

ID gène: 57610

UniProt: Q6VN20