CD207 anticorps (AA 213-223) (AbBy Fluor® 750)
Aperçu rapide pour CD207 anticorps (AA 213-223) (AbBy Fluor® 750) (ABIN5006059)
Antigène
Voir toutes CD207 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 213-223
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Réactivité croisée
- Souris
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Homologie
- Human,Rat
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human CD207
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Isotype
- IgG
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Indications d'application
- IF(IHC-P) 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- CD207 (CD207 Molecule, Langerin (CD207))
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Autre désignation
- Langerin/ CD207
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Sujet
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Synonyms: CLEC4K, C-type lectin domain family 4 member K, Langerin, CD207
Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs), is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.
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ID gène
- 50489
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UniProt
- Q9UJ71
Antigène
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