MEX3A anticorps (C-Term)

N° du produit ABIN500620

Détail du produit anti-MEX3A anticorps

Antigène: MEX3A (Mex-3 Homolog A (MEX3A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEX3A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Rkhd4.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: Rkhd4 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Rkhd4.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur MEX3A

Antigène: MEX3A (Mex-3 Homolog A (MEX3A))

Autre désignation: MEX3A / RKHD4 (MEX3A Produits)

Synonymes: anticorps RKHD4, anticorps MEX-3A, anticorps 2700083E18Rik, anticorps Gm411, anticorps Rkhd4, anticorps mex-3 RNA binding family member A, anticorps mex-3 RNA binding family member A L homeolog, anticorps mex3 RNA binding family member A, anticorps MEX3A, anticorps mex3a.L, anticorps Mex3a

Sujet: Rkhd4, also known as MEX3A is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd4, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. While Rkhd2 has been suggested to be associated with susceptibility to essential hypertension type 8, the function of Rkhd4 remains unknown. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.Synonyms: RING finger and KH domain-containing protein 4, RNA-binding protein MEX3A

ID gène: 92312

UniProt: A1L020