DLGAP1 anticorps (Center)
Aperçu rapide pour DLGAP1 anticorps (Center) (ABIN500652)
Antigène
Voir toutes DLGAP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Specificité
- This antibody detects SAPAP1. It will not cross-react with other SAPAP proteins.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, mouse, rat
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Purification
- Peptide affinity chromatography
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Immunogène
- SAPAP1 antibody was raised against a 18 amino acid peptide from near the center of human SAPAP1.
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))
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Autre désignation
- DLGAP1 / SAPAP1
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Sujet
- SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). At least three isoforms of SAPAP1 are known to exist.Synonyms: DAP-1, DAP1, Disks large-associated protein 1, GKAP, Guanylate kinase-associated protein, PSD-95/SAP90-binding protein 1, SAP90/PSD-95-associated protein 1
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ID gène
- 9229
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NCBI Accession
- NP_001003809
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UniProt
- O14490
Antigène
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