SLFN12 anticorps (C-Term)

N° du produit ABIN500746

Cet anticorps Lapin Polyclonal détecte spécifiquement SLFN12 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SLFN12 anticorps (C-Term) (ABIN500746)

Antigène: SLFN12 (Schlafen Family Member 12 (SLFN12))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLFN12 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-SLFN12 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: SLFN12 antibody was raised against a 12 amino acid peptide from near the carboxy terminus human SLFN12.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur SLFN12

Antigène: SLFN12 (Schlafen Family Member 12 (SLFN12))

Autre désignation: SLFN12

Sujet: Despite being first described several years ago, the roles of the Schlafen (SLFN) family of proteins remain largely unknown. The SLFN genes are preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. It is thought that many play roles in cell growth, hemopoietic cell differentiation, and T cell development and maturation. Most members contain at least one divergent AAA domain (AAA_4) that may play a role in ATP binding. Although also known as SLFN3, a Schlafen family member that may be a marker of T cell activation, human SLFN12 has relatively low homology to SLFN3 in other species. Loss of the SLFN12 gene due to deletion is associated with Kabuki syndrome, a multiple congenital anomaly syndrome, suggesting SLFN may play a role in this genetic condition.Synonyms: Schlafen 12, Schlafen family member 12, Schlafen12

ID gène: 55106

NCBI Accession: NP_060512

UniProt: Q8IYM2