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SPRED2 anticorps (Center)

Cet anticorps Lapin Polyclonal détecte spécifiquement SPRED2 dans WB et EIA. Il présente une réactivité envers Humain.
N° du produit ABIN500800

Aperçu rapide pour SPRED2 anticorps (Center) (ABIN500800)

Antigène

Voir toutes SPRED2 Anticorps
SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

Reactivité

  • 20
  • 20
  • 16
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 27
  • 4
Lapin

Clonalité

  • 28
  • 3
Polyclonal

Conjugué

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SPRED2 est non-conjugé

Application

  • 14
  • 14
  • 13
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 15
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Specificité

    This antibody detects SPRED2. It is predicted to have no cross-reactivity to Spred1 or Spred3.

    Réactivité croisée (Details)

    Species reactivity (tested):Human

    Purification

    Peptide affinity chromatography

    Immunogène

    Spred2 antibody was raised against a 13 amino acid peptide near the center of the human Spred2.

    Isotype

    IgG
  • Indications d'application

    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS containing 0.02 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène

    SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

    Autre désignation

    SPRED2

    Sujet

    Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist.Synonyms: MGC163164, Spred-2, Sprouty-related EVH1 domain containing 2

    ID gène

    200734

    NCBI Accession

    NP_861449
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