SPRED2 anticorps (Center)
Aperçu rapide pour SPRED2 anticorps (Center) (ABIN500800)
Antigène
Voir toutes SPRED2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Specificité
- This antibody detects SPRED2. It is predicted to have no cross-reactivity to Spred1 or Spred3.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Peptide affinity chromatography
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Immunogène
- Spred2 antibody was raised against a 13 amino acid peptide near the center of the human Spred2.
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Isotype
- IgG
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Indications d'application
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))
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Autre désignation
- SPRED2
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Sujet
- Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist.Synonyms: MGC163164, Spred-2, Sprouty-related EVH1 domain containing 2
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ID gène
- 200734
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NCBI Accession
- NP_861449
Antigène
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