SRPX anticorps (N-Term)

N° du produit ABIN500807

Détail du produit anti-SRPX anticorps

Antigène: SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRPX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: SRPX1 antibody was raised against a 13 amino acid peptide from near the amino terminus of human SRPX1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.25 - 0.5 μg/mL. Immunhistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur SRPX

Antigène: SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

Autre désignation: SRPX / ETX1 (SRPX Produits)

Synonymes: anticorps DRS, anticorps ETX1, anticorps SRPX1, anticorps drs, anticorps drs-1, anticorps drs-2, anticorps mDRS-1, anticorps mDRS-2, anticorps Drs, anticorps sushi repeat containing protein, X-linked, anticorps sushi-repeat-containing protein, anticorps sushi-repeat-containing protein, X-linked, anticorps SRPX, anticorps Srpx

Sujet: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.Synonyms: Sushi repeat-containing protein SRPX

ID gène: 8406

NCBI Accession: NP_006298