ST3GAL6 anticorps (C-Term)

N° du produit ABIN500813

Détail du produit anti-ST3GAL6 anticorps

Antigène: ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ST3GAL6 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Specificité: This antibody detects ST3GAL6.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse and Rat

Purification: Peptide Affinity Chromatography

Immunogène: ST3gal6 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of Human ST3gal6.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ST3GAL6

Antigène: ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))

Autre désignation: ST3GAL6 (ST3GAL6 Produits)

Synonymes: anticorps SIAT10, anticorps ST3GALVI, anticorps 1700023B24Rik, anticorps AI930218, anticorps AW552396, anticorps Siat10, anticorps St3galVI, anticorps ST3GAL-VI, anticorps ST3 beta-galactoside alpha-2,3-sialyltransferase 6, anticorps ST3GAL6, anticorps St3gal6

Sujet: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.Synonyms: 3-sialyltransferase, 3-sialyltransferase VI, CMP-NeuAc:beta-galactoside alpha-2, SIAT10, ST3Gal VI, ST3GalVI, Sialyltransferase 10, Type 2 lactosamine alpha-2

ID gène: 10402

NCBI Accession: NP_006091

Pathways: Glycosaminoglycan Metabolic Process