STEAP3 anticorps (N-Term)

N° du produit ABIN500823

Cet anticorps anti-STEAP3 est un anticorps Lapin Polyclonal détectant STEAP3 dans WB, IHC (p) et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour STEAP3 anticorps (N-Term) (ABIN500823)

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STEAP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-STEAP3 anticorps

Épitope: N-Term

Specificité: This antibody detects STEAP3 / TSAP6. It does not cross-react with other STEAP proteins.

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogène: STEAP3 antibody was raised against a 15 amino acid peptide from near the amino terminus of human STEAP3.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur STEAP3

Antigène: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Autre désignation: STEAP3 / TSAP6

Sujet: The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction, mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.Synonyms: Dudulin-2, Metalloreductase STEAP3, STEAP-3, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, pH yde

ID gène: 55240

Pathways: Transition Metal Ion Homeostasis