PANK3 anticorps (AA 271-370) (AbBy Fluor® 680)

N° du produit ABIN5008317

Cet anticorps Lapin Polyclonal détecte spécifiquement PANK3 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Rat.

Aperçu rapide pour PANK3 anticorps (AA 271-370) (AbBy Fluor® 680) (ABIN5008317)

Antigène: PANK3 (Pantothenate Kinase 3 (PANK3))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PANK3 est conjugé à/à la AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-PANK3 anticorps (AbBy Fluor® 680)

Épitope: AA 271-370

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PANK3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PANK3

Antigène: PANK3 (Pantothenate Kinase 3 (PANK3))

Autre désignation: PANK3

Sujet:

Synonyms: hPanK3, MGC16863, OTTHUMP00000160961, Pank3, PANK3_HUMAN, Pantothenate kinase 3, pantothenic acid kinase, Pantothenic acid kinase 3.

Background: The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis. Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle. Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration. Localized to the cytoplasm, PANK3 is regulated by feedback inhibition by CoA and its thioesters. PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), resulting in formation of 4?-phosphopantothenate. Closely related to its family members, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver. Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, the only mitochondria targeted human PANK.

ID gène: 79646

Pathways: Ribonucleoside Biosynthetic Process