IL27 Receptor alpha anticorps (C-Term)

N° du produit ABIN500877

Détail du produit anti-IL27 Receptor alpha anticorps

Antigène: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Épitope: C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL27 Receptor alpha est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TCCR / IL27RA at C-term.

Réactivité croisée (Details): Species reactivity (expected):MouseSpecies reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human TCCR precursor. Remarks: The sequence is identical to that of mouse TCCR.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 to 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur IL27 Receptor alpha

Antigène: IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))

Autre désignation: TCCR / IL27RA (IL27RA Produits)

Synonymes: anticorps IL27RA, anticorps CRL1, anticorps IL-27RA, anticorps IL27R, anticorps TCCR, anticorps WSX1, anticorps zcytor1, anticorps IL-27R, anticorps Tccr, anticorps WSX-1, anticorps Wsx1, anticorps interleukin 27 receptor subunit alpha, anticorps interleukin-27 receptor subunit alpha, anticorps interleukin 27 receptor, alpha, anticorps IL27RA, anticorps LOC484907, anticorps Il27ra

Sujet: Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned (1,2). It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1 (1,2). TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a . TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.Synonyms: CRL1, IL-27R-alpha, Interleukin-27 receptor subunit alpha, T-cell cytokine receptor type 1, UNQ296/PRO336, WSX-1, WSX1

ID gène: 9466

NCBI Accession: NP_004834

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response