CD248 anticorps (N-Term)

N° du produit ABIN500887

Cet anticorps Lapin Polyclonal détecte spécifiquement CD248 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CD248 anticorps (N-Term) (ABIN500887)

Antigène: CD248 (CD248 Molecule, Endosialin (CD248))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD248 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-CD248 anticorps

Épitope: N-Term

Specificité: This antibody detects CD248 / TEM1 at N-term. It recognizes only the larger isoform.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Peptide Affinity Chromatography

Immunogène: A 14 amino acid peptide near the amino terminus of the Human TEM1.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD248

Antigène: CD248 (CD248 Molecule, Endosialin (CD248))

Autre désignation: CD248 / TEM1

Sujet: Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion. At least two isoforms of TEM1 are known to exist.Synonyms: CD164L1, Endosialin, Tumor endothelial marker 1

ID gène: 57124

NCBI Accession: NP_065137