ARHGEF17 anticorps (Center)

N° du produit ABIN500893

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGEF17 dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ARHGEF17 anticorps (Center) (ABIN500893)

Antigène: ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF17 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ARHGEF17 anticorps

Épitope: Center

Specificité: This antibody detects ARHGEF17 / TEM4 at center.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: TEM4 antibody was raised against a 18 amino acid peptide near the center of human TEM4.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur ARHGEF17

Antigène: ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))

Autre désignation: ARHGEF17 / TEM4

Sujet: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.Synonyms: 164 kDa Rho-specific guanine-nucleotide exchange factor, KIAA0337, Rho guanine nucleotide exchange factor 17, Tumor endothelial marker 4, p164-RhoGEF, p164RhoGEF

ID gène: 9828

UniProt: Q96PE2