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ARHGEF17 anticorps (Center)

ARHGEF17 Reactivité: Humain WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN500893
  • Antigène Voir toutes ARHGEF17 Anticorps
    ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
    Épitope
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivité
    • 11
    • 9
    Humain
    Hôte
    • 11
    Lapin
    Clonalité
    • 11
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ARHGEF17 est non-conjugé
    Application
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects ARHGEF17 / TEM4 at center.
    Réactivité croisée (Details)
    Species reactivity (tested):Human
    Purification
    Peptide affinity chromatography
    Immunogène
    TEM4 antibody was raised against a 18 amino acid peptide near the center of human TEM4.
    Isotype
    IgG
    Top Product
    Discover our top product ARHGEF17 Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    ARHGEF17 (rho Guanine Nucleotide Exchange Factor (GEF) 17 (ARHGEF17))
    Autre désignation
    ARHGEF17 / TEM4 (ARHGEF17 Produits)
    Synonymes
    anticorps P164RHOGEF, anticorps TEM4, anticorps p164-RhoGEF, anticorps 8030463K16, anticorps AI428794, anticorps AW558066, anticorps BC035332, anticorps mKIAA0337, anticorps Rho guanine nucleotide exchange factor 17, anticorps Rho guanine nucleotide exchange factor (GEF) 17, anticorps ARHGEF17, anticorps Arhgef17
    Sujet
    Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.Synonyms: 164 kDa Rho-specific guanine-nucleotide exchange factor, KIAA0337, Rho guanine nucleotide exchange factor 17, Tumor endothelial marker 4, p164-RhoGEF, p164RhoGEF
    ID gène
    9828
    UniProt
    Q96PE2
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