GPR124 anticorps (C-Term)

N° du produit ABIN500895

Cet anticorps anti-GPR124 Polyclonal Lapin (ABIN500895) détecte spécifiquement GPR124 dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour GPR124 anticorps (C-Term) (ABIN500895)

Antigène: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR124 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-GPR124 anticorps

Épitope: C-Term

Specificité: This antibody detects GPR124 / TEM5 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, rat

Purification: Peptide affinity chromatography

Immunogène: TEM5 antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human TEM5.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur GPR124

Antigène: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Autre désignation: GPR124 / TEM5

Sujet: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.Synonyms: G-protein coupled receptor 124, KIAA1531, Tumor endothelial marker 5

ID gène: 25960

UniProt: Q96PE1