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TIMD4 anticorps (Center)

Cet anticorps Lapin Polyclonal détecte spécifiquement TIMD4 dans WB, IF et EIA. Il présente une réactivité envers Humain et Souris.
N° du produit ABIN500917

Aperçu rapide pour TIMD4 anticorps (Center) (ABIN500917)

Antigène

Voir toutes TIMD4 Anticorps
TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reactivité

  • 36
  • 23
  • 5
  • 2
  • 1
Humain, Souris

Hôte

  • 29
  • 12
  • 9
  • 1
  • 1
Lapin

Clonalité

  • 27
  • 24
  • 1
Polyclonal

Conjugué

  • 35
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Cet anticorp TIMD4 est non-conjugé

Application

  • 28
  • 26
  • 19
  • 12
  • 8
  • 8
  • 7
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • Épitope

    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Specificité

    This antibody detects TIMD4 at center.

    Réactivité croisée (Details)

    Species reactivity (tested):Human, Mouse.

    Purification

    Peptide affinity chromatography

    Immunogène

    TIM-4 antibody was raised against a 16 amino acid peptide from near the center of human TIM-4.

    Isotype

    IgG
  • Indications d'application

    ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS, 0.02 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène

    TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

    Autre désignation

    TIMD4

    Sujet

    The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.Synonyms: T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM-4, TIM4, TIMD-4

    ID gène

    91937

    NCBI Accession

    NP_612388

    Pathways

    Cancer Immune Checkpoints
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