TIMD4 anticorps (Center)

N° du produit ABIN500917

Détail du produit anti-TIMD4 anticorps

Antigène: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Épitope: Center

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMD4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TIMD4 at center.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse.

Purification: Peptide affinity chromatography

Immunogène: TIM-4 antibody was raised against a 16 amino acid peptide from near the center of human TIM-4.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur TIMD4

Antigène: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Autre désignation: TIMD4 (TIMD4 Produits)

Synonymes: anticorps RGD1564516, anticorps MGC99322, anticorps TIMD4, anticorps B430010N18Rik, anticorps TIM-4, anticorps Tim4, anticorps SMUCKLER, anticorps TIM4, anticorps T-cell immunoglobulin and mucin domain containing 4, anticorps T-cell immunoglobulin and mucin domain containing 4 L homeolog, anticorps T cell immunoglobulin and mucin domain containing 4, anticorps Timd4, anticorps TIMD4, anticorps timd4.L

Sujet: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.Synonyms: T-cell immunoglobulin and mucin domain-containing protein 4, T-cell membrane protein 4, TIM-4, TIM4, TIMD-4

ID gène: 91937

NCBI Accession: NP_612388

Pathways: Cancer Immune Checkpoints