TLR11 anticorps (C-Term, Middle Region)

N° du produit ABIN500944

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR11 dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour TLR11 anticorps (C-Term, Middle Region) (ABIN500944)

Antigène: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR11 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-TLR11 anticorps

Épitope: C-Term, Middle Region

Réactivité croisée (Details): Species reactivity (tested):Mouse

Purification: Ion exchange chromatography

Immunogène: TLR11 antibody was raised against a peptide corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11 (GenBank accession no NP_991388).

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 0.5 to 2 μg/mL. Imunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur TLR11

Antigène: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Autre désignation: TLR11

Sujet: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).Synonyms: Gm287, Toll-like receptor 11

ID gène: 239081

NCBI Accession: NP_991388

Pathways: Activation of Innate immune Response