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FNBP1L anticorps (N-Term)

FNBP1L Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN501004
  • Antigène Voir toutes FNBP1L Anticorps
    FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
    Épitope
    • 15
    • 8
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 46
    • 20
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 45
    • 1
    Lapin
    Clonalité
    • 45
    • 1
    Polyclonal
    Conjugué
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FNBP1L est non-conjugé
    Application
    • 21
    • 18
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects FNBP1L at N-term.
    Réactivité croisée (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogène
    TOCA-1 antibody was raised against a 15 amino acid peptide near the amino terminus of the human TOCA-1.
    Isotype
    IgG
    Top Product
    Discover our top product FNBP1L Anticorps primaire
  • Indications d'application
    ELISA. Western blot: 0.5 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène
    FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
    Autre désignation
    FNBP1L (FNBP1L Produits)
    Synonymes
    anticorps C1orf39, anticorps TOCA1, anticorps 2610318I01Rik, anticorps AW548221, anticorps RGD1305386, anticorps Toca-1, anticorps zgc:100923, anticorps toca1, anticorps toca-1, anticorps MGC132162, anticorps fnbp1l, anticorps formin binding protein 1 like, anticorps formin binding protein 1-like, anticorps formin binding protein 1 like L homeolog, anticorps formin binding protein 1 like S homeolog, anticorps FNBP1L, anticorps Fnbp1l, anticorps fnbp1l, anticorps fnbp1l.L, anticorps fnbp1l.S
    Sujet
    Actin reorganization is important for the regulation of neuronal morphology. A protein involved in this process, the transducer of cdc42-dependent actin assembly 1 (TOCA-1) protein, a member of the evolutionarily conserved pombe CDC15 homology (PCH) protein family, is an essential component of the Cdc42 pathway. TOCA-1 binds both N-WASP and Cdc42 and is essential for Cdc42- and PIP2-induced actin polymerization, suggesting that TOCA-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Decreased expression of TOCA-1 significantly enhances neurite elongation in PC-12 cells, its overexpression in the same cells suppresses neurite elongation. It has been suggested that TOCA-1 negatively regulates axon branching by regulating membrane trafficking by regulating membrane trafficking through the F-BAR/EFC domain. Multiple isoforms of TOCA-1 are known to exist.Synonyms: C1orf39, Formin-binding protein 1-like, TOCA1, Transducer of Cdc42-dependent actin assembly protein 1
    ID gène
    54874
    NCBI Accession
    NP_001020119
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