Thymic Stromal Lymphopoietin anticorps (C-Term)

N° du produit ABIN501077

L’anticorps Lapin Polyclonal anti-Thymic Stromal Lymphopoietin a été validé pour WB, IHC (p) et EIA. Il convient pour détecter Thymic Stromal Lymphopoietin dans des échantillons de Humain.

Aperçu rapide pour Thymic Stromal Lymphopoietin anticorps (C-Term) (ABIN501077)

Antigène: Thymic Stromal Lymphopoietin (TSLP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thymic Stromal Lymphopoietin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Thymic Stromal Lymphopoietin anticorps

Épitope: C-Term

Specificité: This antibody detects TSLP at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Peptide affinity chromatography

Immunogène: TSLP antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human TSLP.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur Thymic Stromal Lymphopoietin

Antigène: Thymic Stromal Lymphopoietin (TSLP)

Autre désignation: TSLP

Sujet: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. Despite its predicted molecular weight, TSLP often migrates at a higher molecular weight in SDS-PAGE. At least two differentially spliced isoforms of TSLP are known to exist.Synonyms: Thymic stroma-derived lymphopoietin, Thymic stromal lymphopoietin

ID gène: 85480

NCBI Accession: NP_149024