TFCP2 anticorps (AbBy Fluor® 750)

N° du produit ABIN5011507

L’anticorps Lapin Polyclonal anti-TFCP2 a été validé pour WB et IF (p). Il convient pour détecter TFCP2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TFCP2 anticorps (AbBy Fluor® 750) (ABIN5011507)

Antigène: TFCP2 (Transcription Factor CP2 (TFCP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFCP2 est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-TFCP2 anticorps (AbBy Fluor® 750)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TFCP2C

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TFCP2

Antigène: TFCP2 (Transcription Factor CP2 (TFCP2))

Autre désignation: TFCP2C

Sujet:

Synonyms: Alpha globin transcription factor CP2, CP2, LBP 1C, LBP1C, LSF, SAA3 enhancer factor, SEF, TFCP2, TFCP2C, Transcription factor CP2, Transcription factor LSF, TFCP2_HUMAN.

Background: CP2 family gene products are reported to be involved in a-globin gene expression. Mouse CP2c (also known as a-CP2/CP2/LSF/UBP-1) is a homologue of human LBP-1c with 96 % amino acid sequence identity. CP2c was initially identified as an activator of the mouse a-globin gene, which binds to the consensus DNA-binding sequence CNRG-N6-CNR(G/C) within a promoter element overlapping the CCAAT box. The transcriptional activity of CP2c was increased during induced differentiation of MEL cells and associated globin gene transcription. CP2c is also likely to be involved in regulation of non-globin erythroid-specific genes. It was reported that congenital erythropoietic porphyria was caused by the mutations in GATA-1 and CP2c binding sites within the promoter of the uroporphyrinogen III synthase gene, the fourth enzyme in the heme biosynthetic pathway.

ID gène: 7024