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ZNF536 anticorps (N-Term)

ZNF536 Reactivité: Humain, Souris, Rat WB, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN501163
  • Antigène Voir toutes ZNF536 Anticorps
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    Épitope
    • 8
    • 8
    • 6
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp ZNF536 est non-conjugé
    Application
    • 15
    • 13
    • 13
    • 13
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse, Rat
    Purification
    Affinity chromatography
    Immunogène
    16 amino acid peptide from near the amino terminus of human ZNF536
    Isotype
    IgG
    Top Product
    Discover our top product ZNF536 Anticorps primaire
  • Indications d'application
    ELISA. Western blot at 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    Store the antibody (in aliquots) at -20 °C.
  • Antigène
    ZNF536 (Zinc Finger Protein 536 (ZNF536))
    Autre désignation
    ZNF536 (ZNF536 Produits)
    Synonymes
    anticorps 9630010P11Rik, anticorps Znf536, anticorps mKIAA0390, anticorps RGD1563363, anticorps zinc finger protein 536, anticorps ZNF536, anticorps Zfp536
    Sujet
    ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and b-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.Synonyms: KIAA0390, Zinc finger protein 532, Zinc finger protein 532
    ID gène
    9745
    NCBI Accession
    NP_055532
    Pathways
    Retinoic Acid Receptor Signaling Pathway
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