ZSCAN4 anticorps (C-Term)

N° du produit ABIN501165

Cet anticorps anti-ZSCAN4 Polyclonal Lapin (ABIN501165) détecte spécifiquement ZSCAN4 dans WB, IHC (p) et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ZSCAN4 anticorps (C-Term) (ABIN501165)

Antigène: ZSCAN4 (Zinc Finger and SCAN Domain Containing 4 (ZSCAN4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZSCAN4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-ZSCAN4 anticorps

Épitope: C-Term

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography

Immunogène: 18 amino acid peptide near the carboxy terminus of human ZSCAN4

Isotype: IgG

Information d'application

Indications d'application: ELISA. Immunohistochemistry on paraffin sections. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur ZSCAN4

Antigène: ZSCAN4 (Zinc Finger and SCAN Domain Containing 4 (ZSCAN4))

Autre désignation: ZSCAN4

Sujet: Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintenance and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.Synonyms: ZNF494, Zinc finger and SCAN domain-containing protein 4, Zinc finger protein 494

ID gène: 201516

NCBI Accession: NP_689890