ZBTB46 anticorps (AbBy Fluor® 750)

N° du produit ABIN5012639

Cet anticorps anti-ZBTB46 est un anticorps Lapin Polyclonal détectant ZBTB46 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ZBTB46 anticorps (AbBy Fluor® 750) (ABIN5012639)

Antigène: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB46 est conjugé à/à la AbBy Fluor® 750

Application: Western Blotting (WB)

Détail du produit anti-ZBTB46 anticorps (AbBy Fluor® 750)

Réactivité croisée: Souris

Homologie: Human,Rat,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ZBTB46

Antigène: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Autre désignation: ZBTB46/ BTBD4

Sujet:

Synonyms: BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing 46, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340, ZBT46_HUMAN.

Background: BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

ID gène: 140685