ZNRF1 anticorps (AbBy Fluor® 680)

N° du produit ABIN5012802

Cet anticorps Lapin Polyclonal détecte spécifiquement ZNRF1 dans IF (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ZNRF1 anticorps (AbBy Fluor® 680) (ABIN5012802)

Antigène: ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNRF1 est conjugé à/à la AbBy Fluor® 680

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-ZNRF1 anticorps (AbBy Fluor® 680)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ZNRF1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ZNRF1

Antigène: ZNRF1 (Zinc and Ring Finger Protein 1 (ZNRF1))

Autre désignation: ZNRF1

Sujet:

Synonyms: E3 ubiquitin protein ligase ZNRF1, E3 ubiquitin-protein ligase ZNRF1, Nerve injury gene 283, Nerve injury induced gene 283 protein, Nerve injury-induced gene 283 protein, NIN283, Rnf42, Zinc and ring finger 1, zinc and ring finger protein 1, zinc finger and ring finger protein 1, Zinc/RING finger protein 1, ZNRF 1, znrf1, ZNRF1_HUMAN, Zrfp1.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. ZNRF1 (zinc and ring finger 1), also known as NIN283, is a 227 amino acid protein that contains one RING-type zinc finger and localizes to the lysosome and the endosome, as well as to cytoplasmic vesicles and the peripheral membrane. Expressed primarily in nervous system tissue, but also present in testis and thymus, ZNRF1 functions as an E3 ubiquitin-protein ligase that is thought to play a role in the establishment and maintenance of neuronal plasticity. Multiple isoforms of ZNRF1 exist due to alternative splicing events.

ID gène: 84937