Elastase anticorps

N° du produit ABIN5026899

Détail du produit anti-Elastase anticorps

Antigène: Elastase

Reactivité: Mammifères

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp Elastase est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Agglutination (AGG)

Attributs du produit: IgY-antibody

Purification: Precipitation with ammoniumsulfate , dialyse and fitration

Immunogène: raw, native protein

Isotype: IgY

Information d'application

Indications d'application: Perform a chessboard titation before the first application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, 0.1 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Détails sur Elastase

Antigène: Elastase

Abstract: Elastase Produits

Sujet: Secreted by neutrophils and macrophages during inflammation, elastase is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity, destroys bacteria and host tissue. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. It is also an important protease enzyme that when expressed aberrantly can cause emphysema or emphysematous changes. This involves breakdown of the lung structure and increased airspaces.