Calretinin anticorps (AA 4-238)
Aperçu rapide pour Calretinin anticorps (AA 4-238) (ABIN5027071)
Antigène
Voir toutes Calretinin (CALB2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 4-238
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Purification
- Protein A Chromatography
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Immunogène
- A partial length recombinant Calretinin protein (amino acids 4-238) was used as the immunogen for this antibody.
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Isotype
- IgG
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Indications d'application
- WB: 1-2 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Calretinin (CALB2) (Calbindin 2 (CALB2))
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Autre désignation
- Calretinin
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Sujet
- Calretinin is a 29-kD intracellular, vitamin D-dependent calcium binding protein that likely has multiple functional roles including intracellular calcium buffering and message targeting. This protein is a member of the EF-hand family of calcium-binding proteins and first identified in the central nervous system. It has also been identified in a wide variety of non-neural cells, both neoplastic and non-neoplastic. In the oncologic arena calretinin is most commonly used as part of a panel in the separation of pleural mesothelioma from poorly differentiated pulmonary adenocarcinomas. While in most cases highly sensitive and specific for mesothelial origin, calretinin positivity has been reported in carcinomas arising in a myriad of other tissues including ovary, testis, adrenal cortex, colon, breast, sinonasal tract, thymus, skin and even soft tissue.
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Poids moléculaire
- 31 kDa
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ID gène
- 794
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UniProt
- P22676
Antigène
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