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Desmoglein 3 anticorps (AA 328-526)

DSG3 Reactivité: Humain IHC Hôte: Souris Monoclonal ABM4A31 unconjugated
N° du produit ABIN5027152
  • Antigène Voir toutes Desmoglein 3 (DSG3) Anticorps
    Desmoglein 3 (DSG3)
    Épitope
    • 15
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 328-526
    Reactivité
    • 66
    • 21
    • 16
    Humain
    Hôte
    • 61
    • 25
    Souris
    Clonalité
    • 60
    • 26
    Monoclonal
    Conjugué
    • 35
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Desmoglein 3 est non-conjugé
    Application
    • 64
    • 35
    • 20
    • 17
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Purification
    Protein G Chromatography
    Immunogène
    A partial length recombinant Desmoglein 3 protein (amino acids 328-526) was used as the immunogen for this antibody.
    Clone
    ABM4A31
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product DSG3 Anticorps primaire
  • Indications d'application
    IHC: 1 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Antigène
    Desmoglein 3 (DSG3)
    Autre désignation
    Desmoglein 3 (DSG3 Produits)
    Synonymes
    anticorps DSG3, anticorps CDHF6, anticorps PVA, anticorps bal, anticorps balding, anticorps desmoglein 3, anticorps DSG3, anticorps Dsg3
    Sujet
    DSG3 (Desmoglein 3) is a calcium-binding transmembrane glycoprotein component of desmosomes, conferring strong cell-cell adhesion. Desmosomes are button-like points of intercellular contact that allow the attachment of cytoskeletal elements to the plasma membrane at sites of cell-cell adhesion. DSG3 is expressed in basal and immediate suprabasal layers of skin. To maintain cell-cell adhesion DSG3 interacts with other desmosomal proteins, such as plakoglobin. Plakoglobin is closely related to Beta-catenin, which is a well-known downstream effector molecule in the canonical Wnt signaling pathway.DSG3 also promotes cancer cell growth and invasion through a plakoglobin-mediated signaling pathway.
    ID gène
    1830
    UniProt
    P32926
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