RNF31 anticorps (AA 780-1020)

N° du produit ABIN5027254

L’anticorps anti-RNF31 Polyclonal Lapin est utilisé pour la détection de RNF31 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour RNF31 anticorps (AA 780-1020) (ABIN5027254)

Antigène: RNF31 (Ring Finger Protein 31 (RNF31))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF31 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNF31 anticorps

Épitope: AA 780-1020

Purification: Protein A Chromatography

Immunogène: A partial length recombinant HOIP/RNF31 protein (amino acids 780-1020) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur RNF31

Antigène: RNF31 (Ring Finger Protein 31 (RNF31))

Autre désignation: HOIP/RNF31

Sujet: RNF31 (ring finger protein 31), also known as HOIP (HOIL-1-interacting protein) is an atypical E3 ubiquitin ligase that belongs to the RBR (RING-between-RING) family of E3 ligases and is the catalytic component of LUBAC (linear ubiquitin chain assembly complex), a multisubunit E3 ligase. Linear ubiquitin chains are assembled by the LUBAC (Linear Ubiquitin Chain Assembly Complex), which plays a critical role in the activation of the NF-kappaB pathway that is involved in various functions, including cell survival and inflammation. RNF31 is essential for the assembly and function of LUBAC and for various processes governing inflammation and immunity in both hematopoietic and nonhematopoietic cells.

Poids moléculaire: 110 Kda

ID gène: 55072

UniProt: Q96EP0