HOXA9 anticorps (AA 63-272)

N° du produit ABIN5027256

Détail du produit anti-HOXA9 anticorps

Antigène: HOXA9 (Homeobox A9 (HOXA9))

Épitope: AA 63-272

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXA9 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant HOXA9 protein (amino acids 63-272) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur HOXA9

Antigène: HOXA9 (Homeobox A9 (HOXA9))

Autre désignation: HOXA9 (HOXA9 Produits)

Synonymes: anticorps HOXA9, anticorps XlHbox-6, anticorps XlHbox6, anticorps hoxa9-A, anticorps xhoxa9, anticorps HOXA-9, anticorps ABD-B, anticorps HOX1, anticorps HOX1.7, anticorps HOX1G, anticorps D6a9, anticorps Hox-1.7, anticorps Hox1r5, anticorps Hoxa7, anticorps homeobox A9, anticorps homeobox protein Hox-A9, anticorps homeobox A9 S homeolog, anticorps homeobox A7, anticorps HOXA9, anticorps LOC745701, anticorps hoxa9, anticorps hoxa9.S, anticorps Hoxa9, anticorps Hoxa7

Sujet: HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide) . In humans,HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients.

Poids moléculaire: 30 kDa

ID gène: 3205

UniProt: P31269