IL1RL2
Reactivité: Humain, Chien, Cheval, Boeuf (Vache), Porc, Lapin
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 2-4 μg/mL
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Antigène
IL1RL2
(Interleukin 1 Receptor-Like 2 (IL1RL2))
Autre désignation
IL-36R
Sujet
IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules.