IPO7 anticorps (AA 1-322)
Aperçu rapide pour IPO7 anticorps (AA 1-322) (ABIN5027310)
Antigène
Voir toutes IPO7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-322
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Purification
- Protein A Chromatography
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Immunogène
- A partial length recombinant Importin 7 protein (amino acids 1-322) was used as the immunogen for this antibody.
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Isotype
- IgG
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Indications d'application
- WB: 1-2 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- IPO7 (Importin 7 (IPO7))
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Autre désignation
- Importin 7
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Sujet
- Importin 7 (IPO7) is a soluble nuclear transport factor that is required for efficient import. It mediates transport of hTERT into the nucleus. Efficient transport also requires the cytoplasmic nucleoporin Nup358, which was previously implicated in nuclear import of a subset of proteins. Importin 7 plays an important role in nuclear protein import either by acting as autonomous nuclear transport receptor, or as an adapter like protein in association with the importin-beta subunit KPNB1. It serves itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism.
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Poids moléculaire
- 115 kDa
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ID gène
- 10527
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UniProt
- O95373
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Pathways
- Protein targeting to Nucleus
Antigène
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