Importin 9 anticorps (AA 840-1041)
Aperçu rapide pour Importin 9 anticorps (AA 840-1041) (ABIN5027316)
Antigène
Voir toutes Importin 9 (IPO9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 840-1041
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Purification
- Protein A Chromatography
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Immunogène
- A partial length recombinant Importin-9 protein (amino acids 840-1,041) was used as the immunogen for this antibody.
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Isotype
- IgG
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Indications d'application
- WB: 0.25-1.0 μg/mL, IHC: 5 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Importin 9 (IPO9)
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Autre désignation
- Importin-9 (Ran-binding protein 9)
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Sujet
- Importin-9 (IPO9) is a molecular transporter and chaperone that belongs to the super-family of karyopherins. It binds primarily to stem-loop structure 1 in IFN-epsilon5'UTR, and negatively impacts mRNA expression. Importins, including Importin-9, are known for their ability to mediate active transport through nuclear pore complexes and effectively suppress the aggregation of their basic import cargoes in polyanionic environments. Importins exert their functions through protein-protein interactions, they recognize nuclear localization signals and prevent protein aggregation by shielding basic patches such as those found in a variety of ribosomal proteins.
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Poids moléculaire
- 115 kDa
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ID gène
- 55705
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UniProt
- Q96P70
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Pathways
- Protein targeting to Nucleus
Antigène
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