IPO9
Reactivité: Humain
WB, ELISA, ICC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 0.25-1.0 μg/mL, IHC: 5 μg/mL
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Antigène
Importin 9 (IPO9)
Autre désignation
Importin-9 (Ran-binding protein 9)
Sujet
Importin-9 (IPO9) is a molecular transporter and chaperone that belongs to the super-family of karyopherins. It binds primarily to stem-loop structure 1 in IFN-epsilon5'UTR, and negatively impacts mRNA expression. Importins, including Importin-9, are known for their ability to mediate active transport through nuclear pore complexes and effectively suppress the aggregation of their basic import cargoes in polyanionic environments. Importins exert their functions through protein-protein interactions, they recognize nuclear localization signals and prevent protein aggregation by shielding basic patches such as those found in a variety of ribosomal proteins.