JMJD5 anticorps (AA 20-220)

N° du produit ABIN5027324

Cet anticorps anti-JMJD5 est un anticorps Lapin Polyclonal détectant JMJD5 dans WB. Adapté pour Humain.

Aperçu rapide pour JMJD5 anticorps (AA 20-220) (ABIN5027324)

Antigène: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JMJD5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-JMJD5 anticorps

Épitope: AA 20-220

Purification: Protein A Chromatography

Immunogène: A partial length recombinant JMJD5 protein (amino acids 20-220) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur JMJD5

Antigène: JMJD5 (Jumonji Domain Containing 5 (JMJD5))

Autre désignation: JMJD5

Sujet: JMJD5 (Jumonji domain-containing protein 5) or commonly called as Lysine-specific demethylase 8 is a histone lysine demethylase that specifically demethylates dimethylated Lys 36 of histone H3 (H3K36me2) thereby activating the target gene. JMJD5 is important for G2/M phase cell cycle progression. JMJD5 is also a potential tumor suppression protein. JMJD5 helps in regulation of cancer proliferation by regulating cyclin-A1. JMJD5 has three isoforms (47, 24, 50 kDa), all localized in nucleus. JMJD5 is weakly expressed in most normal cells but highly expressed in breast cancer cells.

Poids moléculaire: 47 kDa

ID gène: 79831

UniProt: Q8N371

Pathways: Chromatin Binding