JMJD5 anticorps (AA 20-220)
-
- Antigène Voir toutes JMJD5 Anticorps
- JMJD5 (Jumonji Domain Containing 5 (JMJD5))
-
Épitope
- AA 20-220
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp JMJD5 est non-conjugé
-
Application
- Western Blotting (WB)
- Purification
- Protein A Chromatography
- Immunogène
- A partial length recombinant JMJD5 protein (amino acids 20-220) was used as the immunogen for this antibody.
- Isotype
- IgG
- Top Product
- Discover our top product JMJD5 Anticorps primaire
-
-
- Indications d'application
- WB: 2-4 μg/mL
- Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
- Antigène
- JMJD5 (Jumonji Domain Containing 5 (JMJD5))
- Autre désignation
- JMJD5 (JMJD5 Produits)
- Synonymes
- anticorps jmjd5, anticorps JMJD5, anticorps 3110005O21Rik, anticorps Jmjd5, anticorps zgc:173863, anticorps zgc:91962, anticorps RGD1304823, anticorps lysine demethylase 8, anticorps jumonji domain containing 5, anticorps hypothetical protein, anticorps lysine (K)-specific demethylase 8, anticorps KDM8, anticorps PTRG_02386, anticorps MCYG_00400, anticorps CC1G_13927, anticorps PGTG_16928, anticorps kdm8, anticorps Kdm8
- Sujet
- JMJD5 (Jumonji domain-containing protein 5) or commonly called as Lysine-specific demethylase 8 is a histone lysine demethylase that specifically demethylates dimethylated Lys 36 of histone H3 (H3K36me2) thereby activating the target gene. JMJD5 is important for G2/M phase cell cycle progression. JMJD5 is also a potential tumor suppression protein. JMJD5 helps in regulation of cancer proliferation by regulating cyclin-A1. JMJD5 has three isoforms (47, 24, 50 kDa), all localized in nucleus. JMJD5 is weakly expressed in most normal cells but highly expressed in breast cancer cells.
- Poids moléculaire
- 47 kDa
- ID gène
- 79831
- UniProt
- Q8N371
- Pathways
- Chromatin Binding
-