KLF10/TIEG1 anticorps (AA 11-221)

N° du produit ABIN5027328

Détail du produit anti-KLF10/TIEG1 anticorps

Antigène: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Épitope: AA 11-221

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF10/TIEG1 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant KLF10 protein (amino acids 11-221) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur KLF10/TIEG1

Antigène: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Autre désignation: KLF10 (KLF10 Produits)

Synonymes: anticorps EGR-alpha, anticorps EGRA, anticorps TIEG, anticorps TIEG1, anticorps AI115143, anticorps EGR[a], anticorps Egral, anticorps Gdnfif, anticorps Tieg, anticorps Tieg1, anticorps mGIF, anticorps KLF10, anticorps DKFZp459O142, anticorps fc23d01, anticorps wu:fc23d01, anticorps klf10, anticorps Kruppel like factor 10, anticorps Kruppel-like factor 10, anticorps Kruppel-like factor 10 S homeolog, anticorps KLF10, anticorps Klf10, anticorps klf10, anticorps klf10.S

Sujet: Kruppel-like factor 10 (KLF10 ) is a member of the Kruppel-like family of transcription factors, which are known to be involved in anti-proliferative and apoptotic inducing functions following TGF-beta induction. KLF10 plays an important role in the repression of proliferative and hypertrophic pathways, possibly through the actions of PTTG1 (pituitary tumor-transforming gene 1). KLF10 is found to be predominantly expressed in various tissues and its expression is regulated by cytokines and growth factors. Over-expression of KLF10 has been found to induce apoptosis in pancreatic cancer cells. In addition, KLF10 induces apoptosis via a mechanism which involves the formation of reactive oxygen species.

Poids moléculaire: 46 kDa

ID gène: 7071

UniProt: Q13118

Pathways: Stem Cell Maintenance