KLF10/TIEG1 anticorps (AA 11-221)
Aperçu rapide pour KLF10/TIEG1 anticorps (AA 11-221) (ABIN5027328)
Antigène
Voir toutes KLF10/TIEG1 (KLF10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 11-221
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Purification
- Protein A Chromatography
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Immunogène
- A partial length recombinant KLF10 protein (amino acids 11-221) was used as the immunogen for this antibody.
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Isotype
- IgG
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Indications d'application
- WB: 1-2 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))
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Autre désignation
- KLF10
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Sujet
- Kruppel-like factor 10 (KLF10 ) is a member of the Kruppel-like family of transcription factors, which are known to be involved in anti-proliferative and apoptotic inducing functions following TGF-beta induction. KLF10 plays an important role in the repression of proliferative and hypertrophic pathways, possibly through the actions of PTTG1 (pituitary tumor-transforming gene 1). KLF10 is found to be predominantly expressed in various tissues and its expression is regulated by cytokines and growth factors. Over-expression of KLF10 has been found to induce apoptosis in pancreatic cancer cells. In addition, KLF10 induces apoptosis via a mechanism which involves the formation of reactive oxygen species.
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Poids moléculaire
- 46 kDa
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ID gène
- 7071
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UniProt
- Q13118
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Pathways
- Stem Cell Maintenance
Antigène
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