MAFA anticorps (AA 192-353)

N° du produit ABIN5027344

L’anticorps Lapin Polyclonal anti-MAFA a été validé pour WB. Il convient pour détecter MAFA dans des échantillons de Humain.

Aperçu rapide pour MAFA anticorps (AA 192-353) (ABIN5027344)

Antigène: MAFA (Transcription Factor MafA (MAFA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAFA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MAFA anticorps

Épitope: AA 192-353

Purification: Protein A Chromatography

Immunogène: A partial length recombinant Mafa protein (amino acids 192-353) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur MAFA

Antigène: MAFA (Transcription Factor MafA (MAFA))

Autre désignation: Mafa

Sujet: Musculoaponeurotic fibrosarcoma oncogene family A (MafA) is a pancreatic transcriptional factor that is important to pancreatic beta-cell function. It is a member of the musculo-aponeurotic fibrosarcoma oncogene family, a subgroup of the basic leucine zipper transcription factors with homology to the v-Maf oncoprotein. It acts as a transcriptional regulator that promotes the expression of genes important in glucose-induced insulin secretion, such as insulin, glucokinase and glucose transporter protein-2. Mafa is unique in being exclusively expressed at the secondary and principal phase of insulin-expressing cell production during pancreas organogenesis and is the only transcriptional activator present exclusively in islet beta-cells thus may be involved in pathogenesis of diabetes.

Poids moléculaire: 36 kDa

ID gène: 389692

UniProt: Q8NHW3

Pathways: Hormone Transport