MAFA anticorps (AA 192-353)
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- Antigène Voir toutes MAFA Anticorps
- MAFA (Transcription Factor MafA (MAFA))
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Épitope
- AA 192-353
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAFA est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Protein A Chromatography
- Immunogène
- A partial length recombinant Mafa protein (amino acids 192-353) was used as the immunogen for this antibody.
- Isotype
- IgG
- Top Product
- Discover our top product MAFA Anticorps primaire
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- Indications d'application
- WB: 1-2 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Antigène
- MAFA (Transcription Factor MafA (MAFA))
- Autre désignation
- Mafa (MAFA Produits)
- Synonymes
- anticorps RIPE3b1, anticorps hMafA, anticorps RGD1562627, anticorps 2F1-Ag, anticorps MAFA, anticorps MAFA-L, anticorps SMaf1, anticorps mafl, anticorps L-MAF, anticorps MAFL, anticorps Maf, anticorps v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian), anticorps MAF bZIP transcription factor A, anticorps killer cell lectin-like receptor subfamily G, member 1, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A, anticorps v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa, anticorps monocyte to macrophage differentiation-associated, anticorps Mafa, anticorps MAFA, anticorps Klrg1, anticorps mafa, anticorps mafaa, anticorps Mmd
- Sujet
- Musculoaponeurotic fibrosarcoma oncogene family A (MafA) is a pancreatic transcriptional factor that is important to pancreatic beta-cell function. It is a member of the musculo-aponeurotic fibrosarcoma oncogene family, a subgroup of the basic leucine zipper transcription factors with homology to the v-Maf oncoprotein. It acts as a transcriptional regulator that promotes the expression of genes important in glucose-induced insulin secretion, such as insulin, glucokinase and glucose transporter protein-2. Mafa is unique in being exclusively expressed at the secondary and principal phase of insulin-expressing cell production during pancreas organogenesis and is the only transcriptional activator present exclusively in islet beta-cells thus may be involved in pathogenesis of diabetes.
- Poids moléculaire
- 36 kDa
- ID gène
- 389692
- UniProt
- Q8NHW3
- Pathways
- Hormone Transport
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