MBD3 anticorps (AA 1-290)
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- Antigène Voir toutes MBD3 Anticorps
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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Épitope
- AA 1-290
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MBD3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purification
- Protein G Chromatography
- Immunogène
- A partial length recombinant MBD3 protein (amino acids 1-290) was used as the immunogen for this antibody.
- Clone
- ABM14A8
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product MBD3 Anticorps primaire
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anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 79-209) antibody
MBD3 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (Glu279) antibodyMBD3 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) antibodyMBD3 Reactivité: Humain WB, IHC Hôte: Lapin Monoclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 264-291), (C-Term) antibodyMBD3 Reactivité: Humain, Souris WB, IHC (p) Hôte: Lapin Polyclonal RB02375 unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 70-179) antibodyMBD3 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 1-291) antibodyMBD3 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (AA 1-255) antibodyMBD3 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 3 (MBD3) (C-Term) antibodyMBD3 Reactivité: Humain, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- WB: 2-4 μg/mL, IHC: 5 μg/mL, FACS: 0.5 μg/10^6 cells
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS containing 0.05 % BSA, PH 7.4
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- Antigène
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- Autre désignation
- MBD2/MBD3 (MBD3 Produits)
- Synonymes
- anticorps xmbd3, anticorps MGC69548, anticorps MBD3, anticorps DKFZp459N1635, anticorps AI181826, anticorps AU019209, anticorps methyl-CpG binding domain protein 3 S homeolog, anticorps methyl-CpG binding domain protein 3, anticorps mbd3.S, anticorps mbd3, anticorps MBD3, anticorps Mbd3
- Sujet
- MBD2 is a subunit of the NuRD complex that is postulated to mediate gene repression via recruitment of the complex to methylated DNA. This protein binds around 1 kb downstream of the transcription start site of a subset of 400 CpG island promoters that are characterized by the presence of active histone marks, RNA polymerase II (Pol2) and low to medium gene expression levels and H3K36me3 deposition. Methylated MBD2 is involved in silencing methylated tumor suppressor genes as well as activation of pro-metastatic genes. MBD2 also plays a key role in regulating expression of a range of genes that are associated with optimal DC (Dendritic cells) activation and function.
- Poids moléculaire
- 32. 44 kDa
- ID gène
- 53615
- UniProt
- O95983
- Pathways
- Chromatin Binding
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