MEIS1 anticorps (AA 163-352)

N° du produit ABIN5027352

Cet anticorps Lapin Polyclonal détecte spécifiquement MEIS1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour MEIS1 anticorps (AA 163-352) (ABIN5027352)

Antigène: MEIS1 (Meis Homeobox 1 (MEIS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEIS1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MEIS1 anticorps

Épitope: AA 163-352

Purification: Protein A Chromatography

Immunogène: A partial length recombinant MEIS1 protein (amino acids 163-352) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur MEIS1

Antigène: MEIS1 (Meis Homeobox 1 (MEIS1))

Autre désignation: MEIS1

Sujet: Myeloid ecotropoic viral insertion site 1 (MEIS1) is a transcription factor belonging to TALE (three amino acids loop extension) family. The gene for MEIS1 is mapped to human chromosome 2p15. The amino terminus contains binding domains for its interaction partners, the transcription factors HOXA9 and PBX1, followed by a homeobox DNA binding domain and carboxy-terminal transcriptional activation domains. It is expressed in hematopoietic stem and progenitor cells and increases during human megakaryocytic differentiation. MEIS1 plays a role in the normal development of the hematopoietic lineage and is over expressed in a subset of acute myeloid leukemias. Increased MEIS1 expression has also been observed in neuroblastomas and the expression level of the MEIS1 transcript is a prognostic indicator in breast cancer.

Poids moléculaire: 43 kDa

ID gène: 4211

UniProt: O00470

Pathways: Chromatin Binding