MEIS1 anticorps (AA 163-352)

N° du produit ABIN5027352

Détail du produit anti-MEIS1 anticorps

Antigène: MEIS1 (Meis Homeobox 1 (MEIS1))

Épitope: AA 163-352

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEIS1 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant MEIS1 protein (amino acids 163-352) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur MEIS1

Antigène: MEIS1 (Meis Homeobox 1 (MEIS1))

Autre désignation: MEIS1 (MEIS1 Produits)

Synonymes: anticorps meis, anticorps 1323/07, anticorps 1422/04, anticorps CG17117, anticorps Dm-HTH, anticorps Dmel\\CG17117, anticorps HTH, anticorps Hth, anticorps Meis1, anticorps P53, anticorps anon-EST:Liang-2.13, anticorps clone 2.13, anticorps dtl, anticorps hth1, anticorps hth2, anticorps l(3)05745, anticorps l(3)86Ca, anticorps cb224, anticorps id:ibd5078, anticorps meis1.1, anticorps wu:fb38b03, anticorps wu:fc02e11, anticorps wu:fd12a02, anticorps C530044H18Rik, anticorps Evi8, anticorps Meis homeobox 1, anticorps Meis homeobox 1 S homeolog, anticorps homothorax, anticorps Meis homeobox 1 b, anticorps MEIS1, anticorps meis1.S, anticorps Meis1, anticorps hth, anticorps meis1b, anticorps meis1

Sujet: Myeloid ecotropoic viral insertion site 1 (MEIS1) is a transcription factor belonging to TALE (three amino acids loop extension) family. The gene for MEIS1 is mapped to human chromosome 2p15. The amino terminus contains binding domains for its interaction partners, the transcription factors HOXA9 and PBX1, followed by a homeobox DNA binding domain and carboxy-terminal transcriptional activation domains. It is expressed in hematopoietic stem and progenitor cells and increases during human megakaryocytic differentiation. MEIS1 plays a role in the normal development of the hematopoietic lineage and is over expressed in a subset of acute myeloid leukemias. Increased MEIS1 expression has also been observed in neuroblastomas and the expression level of the MEIS1 transcript is a prognostic indicator in breast cancer.

Poids moléculaire: 43 kDa

ID gène: 4211

UniProt: O00470

Pathways: Chromatin Binding