RAX anticorps (AA 100-313)

N° du produit ABIN5027505

Détail du produit anti-RAX anticorps

Antigène: RAX (Retina and Anterior Neural Fold Homeobox (RAX))

Épitope: AA 100-313

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAX est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant RAX protein (amino acids 100-313) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur RAX

Antigène: RAX (Retina and Anterior Neural Fold Homeobox (RAX))

Autre désignation: RAX (RAX Produits)

Synonymes: anticorps MCOP3, anticorps RX, anticorps 7530406A22Rik, anticorps E130303K03Rik, anticorps Rx, anticorps ey-1, anticorps ey1, anticorps RAX, anticorps rx, anticorps rx1, anticorps Rx2A, anticorps Xrax, anticorps Xrx1, anticorps rax, anticorps CG10052, anticorps DRx, anticorps Dmel\\CG10052, anticorps Drx, anticorps E97, anticorps PPH17, anticorps W60, anticorps bk50, anticorps drx, anticorps wom, anticorps Xrx2, anticorps rax-a, anticorps rax1, anticorps rx1a, anticorps rx2a, anticorps retina and anterior neural fold homeobox, anticorps Retinal Homeobox, anticorps retina and anterior neural fold homeobox L homeolog, anticorps retina and anterior neural fold homeobox S homeolog, anticorps RAX, anticorps Rax, anticorps rax, anticorps Rx, anticorps rax.L, anticorps rax.S

Sujet: RAX or PRKRA (retina and anterior neural fold homeobox) is a homeobox-containing transcription factor. It plays an important role in eye development by regulating the initial specification of retinal cells. In the absence of double-stranded RNA, RAX activates EIF2AK2/PKR, so as to phosphorylate EIF2S1/EFI2-alpha leading to inhibition of translation and induction of apoptosis. RAX has been reported to be essential for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Mutations in this gene have been reported in patients with defects in ocular development, including microphthalmia, anophthalmia and coloboma. RAX is expressed in blood, bone, brain, spleen and adipose tissues.

Poids moléculaire: 30 kDa

ID gène: 8575

UniProt: O75569

Pathways: Regulatory RNA Pathways