SOX11
Reactivité: Humain, Rat, Souris, Lapin
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 0.5-1 μg/mL
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Antigène
SOX11
(SRY (Sex Determining Region Y)-Box 11 (SOX11))
Autre désignation
SOX11
Sujet
SOX11 (Sex determining region Y-box 11), located on chromosome 2p25, belong to the family of genes SOXC. It is a transcript factor involved in the embryonic neurogenesis and tissue remodeling, also participating in the control of cell proliferation. It is involved in gastrulation and in malignant diseases. It is expressed in foetal and neoplastic brain tissue, including gliomas (23619925). SOX11 is overexpressed in several solid tumors and in the vast majority of aggressive mantle cell lymphomas (MCLs). Diseases associated with SOX11 include mental retardation, autosomal dominant, 27 and coffin-siris syndrome.