TRBP anticorps (AA 150-366)

N° du produit ABIN5027591

Détail du produit anti-TRBP anticorps

Antigène: TRBP (TARBP2P) (TAR (HIV-1) RNA Binding Protein 2 Pseudogene (TARBP2P))

Épitope: AA 150-366

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRBP est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A Chromatography

Immunogène: A partial length recombinant TRBP protein (amino acids 150-366) was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: WB: 6-7 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur TRBP

Antigène: TRBP (TARBP2P) (TAR (HIV-1) RNA Binding Protein 2 Pseudogene (TARBP2P))

Autre désignation: TRBP (TARBP2P Produits)

Synonymes: anticorps TRBP, anticorps TARBP2P1, RISC loading complex RNA binding subunit pseudogene 1, anticorps TARBP2P1

Sujet: TRBP, also known as TARBP2 (TAR (HIV-1) RNA binding protein 2) is a contributory agent of acquired immunodeficiency syndrome (AIDS). TRBP binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. It also plays a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1 and promotes translation of TAR-containing RNAs independently of EIF2AK2/PKR. Diseases associated with TARBP2 include acquired immunodeficiency syndrome. TARBP2 is highly expressed in adipose tissue, adrenal cortex, adrenal gland, amniotic fluid and amygdala. TRBP exists in two isoforms whereas alternate splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.

Poids moléculaire: 48 KDa

ID gène: 6895

UniProt: Q15633

Pathways: Regulatory RNA Pathways, Ribonucleoprotein Complex Subunit Organization