CCR6 anticorps

N° du produit ABIN5027745

Cet anticorps Rat Monoclonal détecte spécifiquement CCR6 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour CCR6 anticorps (ABIN5027745)

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CCR6 est non-conjugé

Application: Western Blotting (WB)

Clone: ABM40H1

Détail du produit anti-CCR6 anticorps

Purification: Protein G Chromatography

Immunogène: Full length recombinant protein from mCD196 was used as the immunogen for this antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: WB: 2-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Détails sur CCR6

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Autre désignation: mCD196

Sujet: CD196 displays a high degree of genetic homology between mouse and human. Moreover, in both species it is chromosomally segregated from the main chemokine receptor gene cluster. mCD196 is expressed by myeloid DCs (dendritic cells), mature B cells, subpopulations of memory/effector CD4+ and CD8+ T cells, but not plasmacytoid DCs or naï,ve T cells. mCD196 mediates their migration and function via stimulation with its ligand CCL20 (also known as macrophage inflammatory protein (MIP)-3alpha. mCD196 expression has been correlated with stage and prognosis in a variety of cancers including hepatocellular carcinoma, colorectal carcinoma, glioma, and non-small cell lung cancer. It is also believed to play a role in regulation of cancer progression.

Poids moléculaire: 47 kDa

ID gène: 1235

UniProt: P51684

Pathways: cAMP Metabolic Process