BST2 anticorps (AA 1-180)

N° du produit ABIN513817

Cet anticorps Souris Polyclonal détecte spécifiquement BST2 dans WB, IF et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 9+ publications.

Aperçu rapide pour BST2 anticorps (AA 1-180) (ABIN513817)

Antigène: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Reactivité: Humain

Hôte: Souris

Clonalité: Polyclonal

Conjugué: Cet anticorp BST2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BST2 anticorps

Épitope: AA 1-180

Fonction: Mouse polyclonal antibody raised against a full-length human BST2 protein.

Séquence: MASTSYDYCR VPMEDGDKRC KLLLGIGILV LLIIVILGVP LIIFTIKANS EACRDGLRAV MECRNVTHLL QQELTEAQKG FQDVEAQAAT CNHTVMALMA SLDAEKAQGQ KKVEELEGEI TTLNHKLQDA SAEVERLRRE NQVLSVRIAD KKYYPSSQDS SSAAAPQLLI VLLGLSALLQ

Réactivité croisée: Humain

Attributs du produit: Antibody reactive against mammalian transfected lysate.

Immunogène: BST2 (NP_004326.1, 1 a.a. ~ 180 a.a) full-length human protein.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-BST2 (ABIN513817)

Edgar, Manna, Nishimura, Banting, Robinson: "Tetherin is an exosomal tether." dans: eLife, Vol. 5, (2016) (PubMed).

Brinkmann, Nehlmeier, Walendy-Gnirß, Nehls, González Hernández, Hoffmann, Qiu, Takada, Schindler, Pöhlmann: "The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies." dans: Journal of virology, Vol. 90, Issue 24, pp. 11075-11086, (2016) (PubMed).

Yang, Lopez, Exline, Haworth, Cannon: "Lack of adaptation to human tetherin in HIV-1 group O and P." dans: Retrovirology, Vol. 8, pp. 78, (2011) (PubMed).

Gupta, Mlcochova, Pelchen-Matthews, Petit, Mattiuzzo, Pillay, Takeuchi, Marsh, Towers: "Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 49, pp. 20889-94, (2010) (PubMed).

Hauser, Lopez, Yang, Oldenburg, Exline, Guatelli, Cannon: "HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment." dans: Retrovirology, Vol. 7, pp. 51, (2010) (PubMed).

Casartelli, Sourisseau, Feldmann, Guivel-Benhassine, Mallet, Marcelin, Guatelli, Schwartz: "Tetherin restricts productive HIV-1 cell-to-cell transmission." dans: PLoS pathogens, Vol. 6, Issue 6, pp. e1000955, (2010) (PubMed).

Karetnikov, Suomalainen: "Tethered virions are intermediates in the assembly and release of HIV-1 particles." dans: Virology, Vol. 407, Issue 2, pp. 289-95, (2010) (PubMed).

Lopez, Yang, Hauser, Exline, Haworth, Oldenburg, Cannon: "Ebola virus glycoprotein counteracts BST-2/Tetherin restriction in a sequence-independent manner that does not require tetherin surface removal." dans: Journal of virology, Vol. 84, Issue 14, pp. 7243-55, (2010) (PubMed).

Iwabu, Fujita, Kinomoto, Kaneko, Ishizaka, Tanaka, Sata, Tokunaga: "HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes." dans: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 35060-72, (2009) (PubMed).

Détails sur BST2

Antigène: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Autre désignation: BST2

Sujet: Full Gene Name: bone marrow stromal cell antigen 2
Synonyms: CD317

ID gène: 684

NCBI Accession: NM_004335

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response